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A Unique Cause of Photoreceptor Death

Grant number: 1021918 | Funding period: 2012 - 2015

Completed

Abstract

Abnormalities in cells at the back of the eye called photoreceptors are associated with at least 50% of all cases of blindness in this country.This project will examine a novel mechanism of photoreceptor death. In particular, whether abnormalties in support cells at the back of the eye cause photoreceptors to lose contact with their nutrient source and die.

Related publications (3)

Scholarly works icon

The role of histamine in the retina: Studies on the HDC knockout mouse

U Greferath, KA Vessey, AI Jobling, SA Mills, BV Bui, Z He, N Nag, H Ohtsu, EL Fletcher

2014-12-29

The role of histamine in the retina is not well understood, despite it regulating a number of functions within the brain, includin..

Scholarly works icon

Studying age-related macular degeneration using animal models

EL Fletcher, AI Jobling, U Greferath, SA Mills, M Waugh, T Ho, RU De Iongh, JA Phipps, KA Vessey

2014-01-01

Over the recent years, there have been tremendous advances in our understanding of the genetic and environmental factors associate..

Scholarly works icon

Ccl2/Cx3cr1 knockout mice have inner retinal dysfunction but are not an accelerated model of AMD

KA Vessey, U Greferath, AI Jobling, JA Phipps, T Ho, M Waugh, EL Fletcher

2012-01-01

Purpose. The chemokine, Ccl2, and the fractalkine receptor, Cx3cr1, have both been implicated in the pathogenesis of age related m..

University of Melbourne Researchers

Erica Fletcher's Profile Picture
Erica Fletcher

Una Greferath's Profile Picture
Una Greferath

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